Diabetes Essay Example | Topics and Well Written Essays - 1250 words

Diabetes - Essay Example e discovered numerous advantages for the diabetes patient in maintaining a stable exercise routine as well as the most beneficial degree of physical involvement and frequency of physical activity, but each of these realizations could have an impact on best practices for physical therapists in working with diabetic patients. In â€Å"Metallothionein-Mediated Antioxidant Defense System and Its Response to Exercise Training Are Impaired in Human Type 2 Diabetes† (Scheede-Bergdahl 2005), the authors discuss the importance of metallothioneins I and II (MT 1) as part of the antioxidant defense system and its relationship to exercise in the diabetic patient. Previous studies regarding these antioxidants have indicated that exercise has only beneficial effects on the production of MT 1, but the research team noticed that none of the studies had actually been conducted on people with Type 2 Diabetes. Further evidence had suggested the possibility that these important chemicals are reduced with exercise in persons with Type II Diabetes. During the study, it was confirmed that levels of MT 1 are increased in the skeletal muscle tissue and plasma of healthy individuals who have participated in a regular exercise program. Participants who had Type 2 Diabetes showed no corresponding increases thou gh. While the study was careful to note that there were no increases or decreases in MT 1 levels in the skeletal musculature in these patients, it was also noted that levels were decreased somewhat in the plasma levels. Decreased MT 1 can lead to oxidative stress, which â€Å"contributes to the development and acceleration of related conditions such as nephropathy, neuropathy, retinopathy and macro- and microvascular damage† (Scheede-Bergdahl 2005). At the same time, tissue samples taken from patients with Type 2 Diabetes indicated increased oxidative stress from the control group with tissue appearing more susceptible to damage. As further research is conducted as to

Choose one fromTOTAL QUALITY MANAGEMENT or NEW PRODUCT OR NEW SERVICE Essay

Choose one fromTOTAL QUALITY MANAGEMENT or NEW PRODUCT OR NEW SERVICE INTRODUCTION (NPI) orLEAN MANAGEMENT - Essay Example The engine and the accessories are all out-sourced from about 80 suppliers. The engine supplier is located about 100 Km away but the accessory suppliers are scattered all over the country There is a paint shop but the company uses a contractor to do the jobs with his own labour. 2. There is either a shortage or excess of raw materials at Production Assembly Line as the company works on basis of Material Requirement Planning (MRP) and is dependant on supplier offering delivery dates 3. Movement within the plant is slow and not smooth. Apart from the main conveyor Belt there are few conveyor belts and component feeding is mostly manual. There are only 3 forklift trucks, one for each Machine shop. As a result of above there are Erratic Dispatches. The dealers complain of missing delivery dates for their customers. Despite having fixed quotas for 50 dealerships the company is unable to forecast its requirements. This shows complete ignorance of how to use data and information for production planning. There is no consistency in Production plan. It is made weekly as per demand pressure without considering availability of capacity or raw materials. The Material Requirement Planning (MRP) does not take into consideration the available capacity and schedules resulting in either excess raw materials or shortage of raw materials at production head and elsewhere. Resources are not adequately available for Production resulting in delays within the operation Many movements within same section and between sections are manual as there is a shortage fork-lift trucks. No attention has been paid to installation of conveyers within sections and adding more forklift trucks between sections. Despite the equipment being relatively new breakdowns occur due to non existence of Preventive Maintenance Plans and non availability of spares in time Supply chain is not synchronized with Production hence raw material arrival does not match Production requirements. The